Sublingual immunotherapy in Japan
- 奏良 澁谷
- Jan 22
- 2 min read

1. History and current status of sublingual immunotherapy in Japan
In Japan, sublingual immunotherapy for cedar pollen allergy became covered by insurance in 2014, and treatment for dust mite allergies was added in 2015. In 2018, the age range for sublingual immunotherapy for cedar pollen allergy was expanded to include those 5 years of age and older, making it possible to treat children as well.
2. Treatment effectiveness and duration
Sublingual immunotherapy is recommended to be continued for about three years , and it is said that the longer the treatment period, the more effective it is. Some people feel the effects in the first year, but the effects vary from person to person and may take several months to several years. Approximately 70-80% of patients report improvement in symptoms, but 20-30% may not see any effect.
3. Side effects and precautions
Side effects such as stomatitis, tongue swelling, and itching and discomfort in the mouth have been reported during treatment. In rare cases , serious reactions such as anaphylactic shock may occur, so it is important to start treatment under the guidance of a doctor and to visit a medical institution immediately if you notice any abnormalities.
4. Treatment availability
Sublingual immunotherapy is becoming increasingly popular in Japan, and as of 2023, it is being widely used for patients with cedar pollen allergy and dust mite allergic rhinitis. In particular, its expanded indications for children have contributed to the improvement of allergic symptoms in children.
summary
Sublingual immunotherapy is expected to be a cure for allergic rhinitis in Japan. Because the treatment period is long, patients are required to continue the treatment patiently, but it is expected to improve symptoms and quality of life. When considering treatment, it is important to consult thoroughly with a specialist and create a treatment plan that suits your symptoms and lifestyle .
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